Publications
+ 2019
+ 2018
+ 2017
February
Orthopaedic Journal of Sports Medicine
Clinical study of Ortho-ATI® treatment in patients with chronic gluteal tendinopathy with symptom duration greater than six months, and failure to respond to conservative treatments, including corticosteroid injection. Ortho-ATI® treatment significantly improved clinical outcomes such as pain and disability at 12 and 24 months post treatment.
+ 2016
November
Orthopaedic Journal of Sports Medicine
Lateral Elbow Tendinopathy: Development of a Pathophysiology-Based Treatment Algorithm.
Scientific review article that describes the stages of pathology of tennis elbow. Provides evidence-based, graded treatment principles and associated treatment options for each stage of pathology.
+ 2015
October
Journal of Orthopaedic Proceedings
Bone substitute with gentamycin leads to new bone cells and growth. Clinical observations with rapid bone formed in the bone substitute, and in some cases in the muscle, are a consequence of both leakage of bone active proteins and also from cells coming from the overlaying muscle interacting with the bone substitute
April
American Journal of Sports Medicine
This was a clinical study of Ortho-ATI® in patients with tennis elbow, whose symptom duration was greater than six months, and failed to respond to conservative treatments, including corticosteroid injection. Ortho-ATI® treatment significantly improved clinical function (pain, disability and grip strength) and tendon structure for up to 5 years after treatment.
+ 2014
June
EFORT Congress - London
ATI significantly improved clinical outcome in patients with chronic gluteal tendinopathy at 24 months. We remain guarded about the level of efficacy given the small sample size, however this study has shown promise to plan a larger randomised controlled study.
+ 2013
September
American Journal of Sports Medicine
In this study, patients with chronic LE who had previously undergone an unsuccessful full course of nonoperative treatment showed significantly improved clinical function and structural repair at the origin of the common extensor tendon after ATI. This novel treatment is encouraging for the treatment of tendinopathy and warrants further evaluation.
January
BMJ Case Reports
In this clinical case study of Ortho-ATI® treatment for rotator cuff injury in an elite gymnast, the patient reported substantial improvements in pain and function at one year after treatment. MRI scan showed that the tendinopathy had improved with complete healing of the tendon tear.
+ 2011
June
Journal of Tissue Engineering - Part A
Autologous tenocyte treatment (ATT) improved tendon remodeling, histological outcomes, collagen content, and tensile strength of tendinopathic Achilles tendons. This study suggests ATT may be a useful treatment of chronic Achilles tendinopathy.
+ 2010
June
Journal of Shoulder and Elbow Surgery
This study demonstrated that cell death occurs in the ECRB tendon in chronic lateral epicondylitis. The markedly elevated cell death rate in the grade II cell matrix may be responsible for the decrease in cellularity and further deterioration of collagen quality seen in end-stage grade III matrix. This eventually compromised the tendon's ability to maintain its integrity and resulted in tendon tear. The study suggests cell death plays an important role in the development of tendon degeneration in chronic lateral epicondylitis.
+ 2007
June
Journal of Tissue Engineering
This study suggests the implantation of autologous tenocytes on collagen-based bioscaffolds results in better rotator cuff tendon healing and remodeling than with the implantation of bioscaffold alone.